• Treatment Stem Cells
  • Category Age-Related Diseases

What are stem cells?

Stem cells are already naturally a part of the human repairing system. Also, they are predecessors of all cells in our body.

They are non-specialized. Also, they can become exactly the same as the cells of certain tissues and organs. Therefore, they are the only cells of a human organism that have the ability to differentiate into different tissue-specific cells.

Modern and revolutionary medicine of today uses this ability to achieve the reparation of tissues as well as organs. In that way, they are able to reverse the damage in the organism.

Stem cells replace, regrow, rejuvenate and, also, repair on a cellular level. They are the building blocks from which all healing of the body stems.

The usage of stem cells in medicine

Stem cell therapy is an intervention strategy that introduces new adult stem cells into damaged tissue in order to treat a disease or injury.

Unlike a regular cell, which can only replicate to create more of its own kind of cells, a stem cell can make any one of the 220 different cells in the human body.

Of course, stem cells are one of the most powerful discoveries of modern medicine which are able to change how we see the treatment of many diseases. Also, they may give people health, youth, strength, longevity or even the last chance to live.

Impressive performance and capabilities of these cells can make your immune system and metabolic state stable. In like manner, they make you resistant to pathological agents from the environment which would in combination with stress make your body susceptible to many diseases.

Once stem cells are enriched and their number enlarged during the treatment, they improve both symptoms of the disease and overall health. Stem cells have a unique capability to find a damaged area inside an organism and, also, repair it.

Stem cell treatments and expected results:

  • Sports injuries
  • Allergies and sinusitis
  • Hepatitis
  • Osteoporosis
  • Diabetes
  • Sexual dysfunction
  • Anti-aging procedures
  • Face, body, and organs rejuvenating
  • Increasing general well-being
Stem Cells
Stem Cells

Types of stem cells

There are two types of stem cells which can be used in a stem cell treatment:

  • Autologous – from the patient’s own body (Bone marrow, Adipose tissue stem cells)
  • Allogenic – donor stem cells

What is the process?

The whole treatment in 4 simple steps:

  • Harvesting your own stem cells from your fat
  • Separation of stem cells from fat
  • Activation of stem cells
  • Inserting stem cells through infusion

IM Clinic process

IM Clinic specializes in Autologous, bone marrow and adipose tissue-derived stem cells which are extracted from the lower abdominal area of the patient’s body.

The whole process is quick, non-invasive and effective, done under local anesthesia and combined with intravenous sedation. In that way, our patients may avoid all risks associated with general anesthesia and intubation.

With modern, specialized equipment used by the experienced stem cell specialist team, these procedures are easy to perform.

Iliac bone is only 1-2 cm under the skin, so by using clear anatomical orienteers, the needle aspiration of bone marrow is done in approximately 15 minutes.

The most commonly-used cells are adipose-derived stem cells, located in the patient’s fat, so they can be easily extracted from the lower abdominal area through a simple process of mini-liposuction. The patient is awake after the process of harvesting, and because the whole process is done using only a needle, the surrounding tissue trauma is minimal.

The main advantage

  • The lack of risk of immune rejection of the therapy
  • Disease transmission
  • The whole process duration is one single day

Bone marrow stem cells

It is hard to imagine modern regenerative medicine without the application of bone marrow stem cells.

Conducting more than 1000 clinical studies in 100 000 patients, scientists have discovered that stem cells not only regenerate damaged or inactive cells but also play additional roles. Namely, stem cells use special signal molecules, growth factors, interleukins to regulate and, also, to control the processes like inflammation, cellular metabolism and intercellular communication in the structure of tissues and organs.

Stem Cells

Usage of bone marrow stem cells

  • Sports medicine – The application of stem cells significantly reduces the recovery process after the rupture of the muscles and ligaments
  • Orthopedics – Immediately after the first treatment, the pain intensity decreases and the mobility improves. After two to three months, by using magnetic resonance, the beginning of the regeneration of the joint surface can be observed
    • Osteoarthritis
    • Degenerative joint diseases
    • Cartilage damage
  • Rheumatoid arthritis, Crohn’s disease, ulcerative colitis, and other inflammatory conditions which are by their nature autoimmune diseases. Stem cell therapy often allows patients to enter stable remission and stop using corticosteroids and methotrexate
  • Hyperactivity in autism as well as spasticity in children’s cerebral palsy, including multiple sclerosis, as the result of a stroke
  • Parkinson’s disease and dementia – The patient’s mental state improves, sleep normalizes, the confusion of consciousness and occurrence of hallucinations decrease
  • Anti-aging, aesthetic medicine and cosmetology – By applying stem cell therapy to the skin of the face, the neck and the hand, the number and visibility of wrinkles are reduced, the size of undereye circles as well and skin is tighter. Hydration improves, and the skin is glowing
  • Type 2 diabetes – Stem cell administration helps with insulin resistance. It can also reduce the dose of the medication needed. In some cases, a patient can stop using medicaments altogether. Stem cell treatment reduces systemic inflammation, caused by diabetes
  • Positive effect on the on-blood vessels and nerves increases sensitivity
  • The vision improves
  • The patient can feel the new life energy. Also, there is no need to rest during the day
  • Significantly improves libido and erectile function

Examples

  • Hematopoietic stem cells give rise to blood cells. They are present in bone marrow and also in blood. The body uses them to produce erythrocytes, thrombocytes, leukocytes and, also, the cells of the immune system. The transplantation of these cell types in hematology has virtually replaced a bone marrow transplant
  • Mesenchymal stromal cells are harvested from different body regions (adipose tissue, skin, dental gum tissue, bone marrow). These cells have the ability to divide and differentiate. They are widely and successfully usable in orthopedics, sports medicine, as well as treating burns and in reconstructive surgeries.

Adipose stem cells

The science and medicine have acquired the skills which help isolate particular types of stem cells but are still unable to completely control their activity.

Those are embryonic (fetal) cells and IPS cells (induced pluripotent cells). These cells can grow and differentiate to give any type of tissue but are not safe to use.

Therefore, their application for medical purposes is strictly forbidden. Medical experts are confirming the safety of all cell types that are applying in medicine.

Three stages for the procedure of harvesting stem cells

    • Extracting material

Experts are doing this in local anesthesia or in sedation. The special tumescent Klein solution is introducing under the skin. The application leads to the swelling of the adipose tissue as well as the constriction of blood vessels. After 15-20 minutes, a trained specialist uses a thin cannula with a special technique to collect adipose tissue under sterile conditions.

    • Processing

In a laboratory, a biologist purifies adipose tissue and starts the process of extracting a special fraction from the SVF sample (stromal vascular fraction). In order to isolate the tissue, doctors are using a special method.

Doctors are extracting SVF fraction from the rest of the fraction in three hours. An SVF fraction consists of a special mix of cells which have a good regenerative potential. Among cells in this fraction, there are progenitor cells, preadipocytes, endothelial cells, fibroblasts, mesenchymal stem cells.

Forming of the culture of mesenchymal stem cells derived from adipose tissue. Doctors are cultivating the cells in special bottles or cellular fabrics. The walls of the bottles and the MSC membranes have adhesive properties, so MSC cells can bond to walls.

Other cell types remain in the liquid cellular layer. Doctors are removing them when the nutritive medium is replaced. Under the conditions that allow for cells to divide, the forming of cell culture begins. The process takes between 6 to 8 weeks and provides 10 therapeutic doses.

Doctors are testing cells for sterility, non-pyrogenicity, imunophenotypization, and genome stability.

    • Application of cells

Depending on the indications, the methods of applying cells can vary.

When treating joints and ligaments, doctors are introducing the cells by using ultrasound or fluoroscopic navigation.

In chronical conditions of the respiratory system, we use the inhalation method. Also, in certain neurological conditions, we use the intrathecal and intranasal application of cells.

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